Osseointegration allows for the direct attachment of an external prosthesis to the skeleton through the surgical implantation of intramedullary device.
Historically osseointegration was first introduced as a two-stage procedure. This approach involved implanting a press fit intramedullary component followed by a 6-8 week period of passive healing. After this time a second surgery was needed to create an opening in the skin or “stoma” as it is commonly called, insertion of dual cone and external components. After this, rehabilitation would be commenced.
Since 2014 Professor Al Muderis modified the surgical technique and developed a new implant design which facilitated the ability to perform single-stage surgery without compromising outcomes. This has resulted in eliminating the need for a second operation and the associated risks, improved soft tissue management, faster rehabilitation, earlier return to work and lower overall costs.

No more sweating, rubbing, bruising, chafing or discomfort resulting from the socket.
Thanks to a more stable and natural connection between the prosthetic and the bone.
Increased muscle use and control allow a more natural gait with increased range of motion.
Full limb control with direct mechanics and restored proprioception.
An accelerated surgical and rehabilitation program reduces the overall recovery time to 4-6 weeks.
Regular socket re-fittings are no longer required which can represent significant cost savings.
While Osseointegration surgery may bring many benefits leading to an improved quality of life, it still requires a surgical procedure. Like any medical treatment, there are risks that need to be considered before having the surgery. Here are some of the common risks to be aware of when considering Osseointegration surgery:
1. Infection: One of the most common risks associated with osseointegration surgery is the risk of infection. Since the surgery involves inserting a titanium implant into the bone through an opening of the skin, this will lead to a higher risk of infection and can occur at any time after implantation. While most infections can be effectively managed, an infection may result in implant failure if left untreated.
2. Implant Loosening: Another risk of osseointegration surgery is the failure of the implant to attach properly to the bone. This can occur if the bone is not strong enough to support the implant or if the implant is not inserted correctly. Loosening can also occur if too much load is placed on the implant. In some cases, the implant may need to be removed and reinserted.
3. Complications with anesthesia: The use of anesthesia during surgery carries its own risks, including breathing difficulties and allergic reactions.
5. Nerve or blood vessel damage: The surgical procedure involves the insertion of a metal implant into the bone with significant soft-tissue managemt, which can potentially damage the surrounding nerves and blood vessels, leading to pain, numbness, or loss of sensation.
5. Bone Fracture: The force of inserting the implant into the bone during surgery may cause the bone to become stressed and potentially fracture. After the surgery traumatic events such as a hit or fall could also lead to peri-prosthetic fractures. The management of such fractures are familiar and well documented, and available from most orthopedic trauma centres.
6. Poor healing & Skin irritation: The surgical site may not heal properly due to various reasons such as malnutrition or decreased blood circulation in the area. After the surgical wound has heald, the pressure and rubbing of the prosthetic components against the skin and soft tissue may also cause irritation and sores.
7. Maggot infections: Myiasis is infection with a fly larva, usually occurring in tropical and subtropical areas. The open nature of the stoma presents a risk for some flies to deposit their eggs, which may result in the larvae that hatch to burrow into the stoma or skin area. Proper hygiene of the stoma is therefore very important to prevent and treat maggot infections.
8. Pain: Pain is a common risk associated with any amputation surgery. It may be present during the healing process or persist long-term. Pains can include phantom limb pain, which is a sensation of pain in the missing limb. Stump pain, which is pain in the remaining section of the amputated limb, often realted to neuromas. Amputees also commonly suffer from muscle and joint pain due to an altered gait and increased pressure on other areas of the body.
There may be additional risks based on each individual’s health condition. It’s important to weigh the potential risks and benefits of osseointegration surgery with your doctor to determine if this procedure is right for you. Your doctor can discuss these risks in more detail and provide a personalized assessment of your risk profile.
Patients often inquire if their reason for amputation will make them unsuitable for osseointegration. While the majority of our case cohort have undergone amputation due to trauma, infection – often resulting from joint replacements – is the second leading cause.
It’s important to note that caution must be exercised when considering osseointegration for patients who have undergone radiation therapy at the site of amputation due to its impact on outcomes. Nevertheless, osseointegration can be a viable option for many amputees, offering significant benefits in terms of comfort, mobility, and reduced pain.

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Our mission is to help amputees achieve freedom of mobility and comfort.
